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IFNG, Mouse, FITC, Clone: B27, Abnova™

Catalog No. 89112496 Shop All Abnova Corporation Products
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89-112-496 100 Reactions
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Catalog No. 89-112-496 Supplier Abnova Corporation Supplier No. MAB5864
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Description

Mouse monoclonal antibody raised against recombinant IFNG.

Interferon-gamma (IFNG), or type II interferon, is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFNG in the immune system stems in part from its ability to inhibit viral replication directly, but most importantly derives from its immunostimulatory and immunomodulatory effects. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 (MIM 186940) and CD8 (see MIM 186910) cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops (Schoenborn and Wilson, 2007 [PubMed 17981204]).[supplied by OMIM

Specifications

Antigen IFNG
Applications ELISA
Classification Monoclonal
Clone B27
Conjugate FITC
Description Mouse monoclonal antibody raised against recombinant IFNG.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene IFNG
Gene Alias IFG/IFI
Gene Symbols IFNG
Host Species Mouse
Immunogen Recombinant protein corresponding to human IFNG.
Quantity 100 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3458
Test Specificity human Interferon-gamma (IFN-gamma)1-2. This is a neutralizing antibody. B27 monoclonal antibody has been used for epitope mapping of human IFN-gamma1. The B27 antibody does not bind to denatured IFN-gamma1.
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1 κ
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