IGL@, Mouse, Clone: HP6054, Abnova™

Catalog No.	Quantity
89-109-453	100 μg

Catalog No. 89-109-453 Supplier Abnova Corporation Supplier No. MAB11290

Description

Mouse monoclonal antibody raised against IGL@.

Immunoglobulins recognize foreign antigens and initiate immune responses such as phagocytosis and the complement system. Each immunoglobulin molecule consists of two identical heavy chains and two identical light chains. There are two classes of light chains, kappa and lambda. This region represents the germline organization of the lambda light chain locus. The locus includes V (variable), J (joining), and C (constant) segments. During B cell development, a recombination event at the DNA level joins a single V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase, and by somatic hypermutation, which occurs during B cell maturation in the spleen and lymph nodes. Several V segments and three C segments are known to be incapable of encoding a protein and are considered pseudogenes. The locus also includes several nonimmunoglobulin genes, many of which are pseudogenes or are predicted by automated computational analysis or homology to other species. [provided by RefSeq

Specifications

• Antigen: IGL@
• Applications: Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: HP6054
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against IGL@.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:400) Western Blot (2-5 ug/ml) The optimal working dilution should be determined by the end user.
• Formulation: In 0.2mg/mL PBS (0.05% BSA, 0.05% sodium azide)
• Gene: IGL@
• Gene Alias: IGL/MGC88804
• Gene Symbols: IGL@
• Host Species: Mouse
• Immunogen: Purified human IgG myeloma proteins covalently coupled to polyaminostyren microbeads
• Purification Method: Protein G affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3535
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a