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Description
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq
Specifications
Specifications
| Antigen | IL17A |
| Applications | ELISA |
| Classification | Monoclonal |
| Clone | 5c94 |
| Concentration | 1 ug/uL |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant IL17A. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300) |
| Gene | IL17A |
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