IL1B, Mouse, Clone: 3A6, Abnova™

Mouse monoclonal antibody raised against partial recombinant IL1B.

Supplier:  Abnova Corporation MAB10697

Catalog No. 89-108-898

Description

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq

Specifications

• Antigen: IL1B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Gene: IL1B
• Gene Symbols: IL1B
• Immunogen: Recombinant protein corresponding to human IL1B.
• Regulatory Status: RUO
• Gene ID (Entrez): 3553
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: 3A6
• Description: Mouse monoclonal antibody raised against partial recombinant IL1B.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: IL-1/IL1-BETA/IL1F2
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid