IL2RA, Mouse, APC, Clone: MEM-181, Abnova™

Catalog No.	Quantity
89-111-908	100 Reactions

Catalog No. 89-111-908 Supplier Abnova Corporation Supplier No. MAB4574

Description

Mouse monoclonal antibody raised against native IL2RA.

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. [provided by RefSeq

Specifications

• Antigen: IL2RA
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: MEM-181
• Conjugate: APC
• Description: Mouse monoclonal antibody raised against native IL2RA.
• Dilution: Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: IL2RA
• Gene Alias: CD25/IDDM10/IL2R/TCGFR
• Gene Symbols: IL2RA
• Host Species: Mouse
• Immunogen: Native purified IL2RA from PHA-activated peripheral blood leucocytes.
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3559
• Test Specificity: This antibody reacts with CD25 (Interleukin-2 receptor alpha-chain), a 55 KDa type I transmembrane glycoprotein expressed on activated B and T lymphocytes, activated monocytes/macrophages and on CD4+ T lymphocytes (T regulatory cells); it is lost on resting B and T lymphocytes.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1