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IL6R, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89104743 Shop All Abnova Corporation Products
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89-104-743 50 μL
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Catalog No. 89-104-743 Supplier Abnova Corporation Supplier No. H00003570A01
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Description

Mouse polyclonal antibody raised against a partial recombinant IL6R.

Interleukin 6 (IL6) is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. The protein encoded by this gene is a subunit of the receptor complex for IL6. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq

Sequence: APRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHWVLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS

Specifications

Antigen IL6R
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant IL6R.
Formulation 50% glycerol
Gene IL6R
Gene Accession No. NM_000565
Gene Alias CD126/IL-6R-1/IL-6R-alpha/IL6RA/MGC104991
Gene Symbols IL6R
Host Species Mouse
Immunogen IL6R (NP_000556, 21 a.a. ∽ 120 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3570
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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