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IL7R, Mouse, Clone: ANC8F2, Abnova™

Catalog No. 89113075 Shop All Abnova Corporation Products
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89-113-075 100 μg
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Catalog No. 89-113-075 Supplier Abnova Corporation Supplier No. MAB6938
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Description

Mouse monoclonal antibody raised against recombinant IL7R.

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq

Specifications

Antigen IL7R
Applications Flow Cytometry
Classification Monoclonal
Clone ANC8F2
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant IL7R.
Dilution The optimal working dilution should be determined by the end user.
Formulation In 50mM sodium phosphate buffer, 100mM potassium chloride, 150mM NaCl, pH 7.5 (0.5mg/mL gentamicin sulfate)
Gene IL7R
Gene Alias CD127/CDW127/IL-7R-alpha/IL7RA/ILRA
Gene Symbols IL7R
Host Species Mouse
Immunogen Recombinant protein corresponding to human IL7R.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3575
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG1 κ
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