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Ingegrin αvβ5 Mouse, Alexa Fluor 647, Clone: ALULA, BD

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 565836

Catalog No. BDB565836


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Description

Description

The ALULA monoclonal antibody specifically binds to Integrin alpha v beta 5 ( α v β5 ), which is also known as CD51/β5 . Integrin αvβ5 is widely expressed by fibroblasts, endothelial cells, and vascular smooth muscle cells. It is involved in activation-dependent cell migration and cell adhesion to t he extracellular matrix. Integrin αvβ5 play s a major role in growth factor-induced angiogenesis in response to VEGF and TGF. The αv Integrins, αvβ5 and αvβ3 β5 integrin and functionally block s the interactio n between α v β5 and vitronectin. Although raised against mouse α v β5 , the ALULA antibody crossreacts with human α v β5 .

Specifications

Specifications

Ingegrin αvβ5
ALULA
Alexa Fluor 647
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
IgG2b, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
Integrin alpha v beta 5; αVβ5; CD51/β5
Affinity Purified
Mouse fibroblasts expressing αvβ5
Affinity Chromatography
RUO
Primary
Human, Murine
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