Ingegrin αvβ5 Mouse, Alexa Fluor 647, Clone: ALULA, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 565836

Catalog No. BDB565836

Description

The ALULA monoclonal antibody specifically binds to Integrin alpha v beta 5 ( α v β5 ), which is also known as CD51/β5 . Integrin αvβ5 is widely expressed by fibroblasts, endothelial cells, and vascular smooth muscle cells. It is involved in activation-dependent cell migration and cell adhesion to t he extracellular matrix. Integrin αvβ5 play s a major role in growth factor-induced angiogenesis in response to VEGF and TGF. The αv Integrins, αvβ5 and αvβ3 β5 integrin and functionally block s the interactio n between α v β5 and vitronectin. Although raised against mouse α v β5 , the ALULA antibody crossreacts with human α v β5 .

Specifications

• Antigen: Ingegrin αvβ5
• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Description: Integrin alpha v beta 5; αVβ5; CD51/β5
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human, Mouse
• Isotype: IgG2b κ

• Applications: Flow Cytometry
• Clone: ALULA
• Conjugate: Alexa Fluor 647
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: Mouse fibroblasts expressing αvβ5
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.