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INS, Mouse, Clone: 2B86, Abnova™

Catalog No. 89113315 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-113-315 50 μg
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Catalog No. 89-113-315 Supplier Abnova Corporation Supplier No. MAB8052

Description

Mouse monoclonal antibody raised against INS.

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into two chains (peptide A and peptide B) that are covalently linked via two disulfide bonds. Binding of this mature form of insulin to the insulin receptor (INSR) stimulates glucose uptake. A variety of mutant alleles with changes in the coding region have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq]

Specifications

Antigen INS
Applications ELISA, Immunohistochemistry
Classification Monoclonal
Clone 2B86
Conjugate Unconjugated
Description insulin
Formulation In PBS, pH 7.4 (40% glycerol, 0.05% proclin 300)
Gene INS
Gene Alias ILPR, IRDN
Gene Symbols INS
Host Species Mouse
Immunogen Purified human INS.
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3630
Content And Storage Store at 4°C for three months. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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