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RON (CD136) Mouse anti-Human, Unlabeled, Clone: Zt/g4, BD

Catalog No. BDB565691 Shop All BD Biosciences Products
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BDB565691 0.1 mg
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Catalog No. BDB565691 Supplier BD Biosciences Supplier No. 565691
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Description

Mouse Monoclonal Antibody

The Zt/g4 monoclonal antibody specifically binds to RON, which is also known as CD136, Macrophage-stimulating protein receptor (MSP-Receptor, MSP-R), Macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (MST1R), or Protein-tyrosine kinase 8 (PTK8). RON is a type I transmembrane glycoprotein that belongs to the receptor tyrosine kinase family. It is expressed on cells as a disulfide-linked heterodimer. RON is expressed on macrophages, keratinocytes, erythroblasts and epithelial cells from the skin, lung, kidney, liver, intestine, colon, and bone marrow. RON reportedly regulates many physiological processes including the survival, migration, differentiation, and effector functions of a variety of cell types including epithelial cells, and macrophages. RON binds Macrophage stimulating protein (MSP). Overexpression of RON may contribute to the malignant transformation of epithelial cells.

TRUSTED_SUSTAINABILITY

Specifications

Antigen RON (CD136)
Applications Flow Cytometry, Immunohistochemistry
Classification Monoclonal
Clone Zt/g4
Concentration 0.5mg/mL
Conjugate Unconjugated
Description MSP Receptor; MSP-R; MST1R; p185-Ron; PTK8 protein tyrosine kinase 8; PTK8
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human RON Transfected Cell Line
Purification Method Affinity Purified
Quantity 0.1 mg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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