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Mouse anti-Integrin beta 2/CD18, Clone: 68-5A5, Novus Biologicals™

Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2449630.2MG
Description
Ensure accurate, reproducible results in Flow Cytometry, Immunofluorescence
Integrin beta 2/CD18 Monoclonal antibody specifically detects Integrin beta 2/CD18 in Human samples. It is validated for Flow Cytometry, SDS-Page, Immunofluorescence.Specifications
Integrin beta 2/CD18 | |
Monoclonal | |
0.2 mg/mL | |
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml | |
959 beta subunit precursor)10, CD18 antigen, CD18beta 2, cell surface adhesion glycoprotein (LFA-1, CR3, integrin beta-2, integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1;macrophage antigen 1 (mac-1) beta subunit), integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), LAD, LCAMB, leukocyte cell adhesion molecule CD18, leukocyte-associated antigens CD18/11A, CD18/11B, CD18/11C, MF17, MFI7, P150 | |
Mouse | |
95 kDa | |
0.2 mg | |
Apoptosis, Cytokine Research, Immunology | |
3689 | |
Human | |
Purified |
Flow Cytometry, SDS-Page, Immunofluorescence | |
68-5A5 | |
Unconjugated | |
10mM PBS and 0.05% BSA with 0.05% Sodium Azide | |
ITGB2 | |
Stimulated human leukocytes | |
Protein A or G purified | |
RUO | |
Primary | |
It recognizes a transmembrane glycoprotein of 95kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions. | |
Store at 4C. | |
IgG2a κ |
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