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Description
IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. [provided by RefSeq
Specifications
Specifications
| Antigen | IRF3 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3F10 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant IRF3. |
| Dilution | Western Blot (1:1000-1:3000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (10% glycerol, 0.09% sodium azide) |
| Gene | IRF3 |
| Gene Accession No. | NM_001571 |
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