ITGA1, Mouse, Clone: TS2/7, Abnova™

Mouse monoclonal antibody raised against native ITGA1.

Supplier:  Abnova Corporation MAB5224

Catalog No. 89-112-175

Description

This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq

Specifications

• Antigen: ITGA1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (5 ul of the antibody (neat) to label 10⁶ cells) The optimal working dilution should be determined by the end user.
• Gene: ITGA1
• Gene Symbols: ITGA1
• Immunogen: Native purified ITGA1 from human thymoma cell line HPB-ALL.
• Regulatory Status: RUO
• Gene ID (Entrez): 3672
• Target Species: Human
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
• Clone: TS2/7
• Description: Mouse monoclonal antibody raised against native ITGA1.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: CD49a/VLA1
• Host Species: Mouse
• Quantity: 500 μL
• Primary or Secondary: Primary
• Test Specificity: TS2/7 recognizes the human alpha 1 integrin sub-unit, which forms the VLA-1 heterodimer in association with the beta 1 integrin. VLA-1 is a receptor for collagen and laminin, and is expressed by chronically activated T cells, melanoma cells and smooth muscle cells.
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgG1