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Description
Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq
Specifications
Specifications
| Antigen | ITGAE |
| Applications | Flow Cytometry, Immunohistochemistry (Frozen) |
| Classification | Monoclonal |
| Clone | B-Ly7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against ITGAE. |
| Dilution | The optimal working dilution should be determined by the end user. |
| Formulation | In aqueous buffer (0.09% sodium azide) |
| Gene | ITGAE |
| Gene Alias | CD103/HUMINAE/MGC141996 |
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