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ITGAM, Mouse, APC, Clone: ICRF44, Abnova™

Catalog No. 89112644 Shop All Abnova Corporation Products
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89-112-644 100 Reactions
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Catalog No. 89-112-644 Supplier Abnova Corporation Supplier No. MAB6033
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Description

Mouse monoclonal antibody raised against native ITGAM.

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen ITGAM
Applications Flow Cytometry, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone ICRF44
Conjugate APC
Description Mouse monoclonal antibody raised against native ITGAM.
Dilution Flow Cytometry (10 ul/106 cells) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.09% sodium azide)
Gene ITGAM
Gene Alias CD11B/CR3A/MAC-1/MAC1A/MGC117044/MO1A/SLEB6
Gene Symbols ITGAM
Host Species Mouse
Immunogen Native purified ITGAM from rheumatoid synovial cells and human monocytes.
Quantity 100 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3684
Test Specificity Specificity human CD11b/Mac-1alpha
Target Species Human
Content And Storage Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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