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ITGAM, Mouse, Clone: DCIS1/18, Abnova™

Catalog No. 89112018 Shop All Abnova Corporation Products
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89-112-018 100 μg
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Catalog No. 89-112-018 Supplier Abnova Corporation Supplier No. MAB4966
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Description

Mouse monoclonal antibody raised against ITGAM.

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen ITGAM
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone DCIS1/18
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against ITGAM.
Dilution Flow Cytometry (20 uL/106 cells) The optimal working dilution should be determined by the end user.
Formulation In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
Gene ITGAM
Gene Alias CD11B/CR3A/MAC-1/MAC1A/MGC117044/MO1A/SLEB6
Gene Symbols ITGAM
Host Species Mouse
Immunogen Dendritic cells derived from human monocytes.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3684
Target Species Human
Content And Storage Store in the dark at 4°C. Avoid prolonged exposure to light.
Form Liquid
Isotype IgG2a
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