ITGAM, Mouse, Clone: DCIS1/18, Abnova™

Mouse monoclonal antibody raised against ITGAM.

Supplier:  Abnova Corporation MAB4966

Catalog No. 89-112-018

Description

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: ITGAM
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (20 uL/10⁶ cells) The optimal working dilution should be determined by the end user.
• Gene: ITGAM
• Gene Symbols: ITGAM
• Immunogen: Dendritic cells derived from human monocytes.
• Regulatory Status: RUO
• Gene ID (Entrez): 3684
• Content And Storage: Store in the dark at 4°C. Avoid prolonged exposure to light.
• Isotype: IgG2a

• Applications: Flow Cytometry, Immunofluorescence
• Clone: DCIS1/18
• Description: Mouse monoclonal antibody raised against ITGAM.
• Formulation: In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
• Gene Alias: CD11B/CR3A/MAC-1/MAC1A/MGC117044/MO1A/SLEB6
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid