ITGAM, Mouse, SPRD, Clone: ICRF44, Abnova™

Mouse monoclonal antibody raised against native ITGAM.

Supplier:  Abnova Corporation MAB6034

Catalog No. 89-112-645

Description

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: ITGAM
• Classification: Monoclonal
• Conjugate: SPRD
• Dilution: Flow Cytometry (10 ul/10⁶ cells) The optimal working dilution should be determined by the end user.
• Gene: ITGAM
• Gene Symbols: ITGAM
• Immunogen: Native purified ITGAM from rheumatoid synovial cells and human monocytes.
• Regulatory Status: RUO
• Gene ID (Entrez): 3684
• Target Species: Human
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Frozen)
• Clone: ICRF44
• Description: Mouse monoclonal antibody raised against native ITGAM.
• Formulation: In PBS (0.09% sodium azide)
• Gene Alias: CD11B/CR3A/MAC-1/MAC1A/MGC117044/MO1A/SLEB6
• Host Species: Mouse
• Quantity: 100 Reactions
• Primary or Secondary: Primary
• Test Specificity: Specificity human CD11b/Mac-1alpha
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1