ITGAV, Mouse, Clone: P2W7, Abnova™

Catalog No.	Quantity
89-113-080	100 μg

Catalog No. 89-113-080 Supplier Abnova Corporation Supplier No. MAB6943

Description

Mouse monoclonal antibody raised against native ITGAV.

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq]

Specifications

• Antigen: ITGAV
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
• Classification: Monoclonal
• Clone: P2W7
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native ITGAV.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In 50mM sodium phosphate buffer, 100mM potassium chloride, 150mM NaCl, pH 7.5 (0.5mg/mL gentamicin sulfate)
• Gene: ITGAV
• Gene Alias: CD51/DKFZp686A08142/MSK8/VNRA
• Gene Symbols: ITGAV
• Host Species: Mouse
• Immunogen: Native purified ITGAV from human ocular melanoma cell line (V+B2).
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3685
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG1 κ