ITGAX, Mouse, APC, Clone: BU15, Abnova™

Catalog No.	Quantity
89-111-773	100 Reactions

Catalog No. 89-111-773 Supplier Abnova Corporation Supplier No. MAB4351

Description

Mouse monoclonal antibody raised against native ITGAX.

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq

Specifications

• Antigen: ITGAX
• Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
• Classification: Monoclonal
• Clone: BU15
• Conjugate: APC
• Description: Mouse monoclonal antibody raised against native ITGAX.
• Dilution: Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: ITGAX
• Gene Alias: CD11C/SLEB6
• Gene Symbols: ITGAX
• Host Species: Mouse
• Immunogen: Native purified ITGAX from human dendritic cells of synovial fluid.
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3687
• Test Specificity: This antibody reacts with ITGAX, a 150 KDa integrin expressed mainly on dendritic cells and tissue macrophages.
• Target Species: Canine, Human, Monkey
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1