ITGB2, Mouse, Clone: IB4, Abnova™

Mouse monoclonal antibody raised against native ITGB2.

Supplier:  Abnova Corporation MAB6945

Catalog No. 89-113-082

Description

The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq

Specifications

• Antigen: ITGB2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: ITGB2
• Gene Symbols: ITGB2
• Immunogen: Native purified ITGB2 from human peripheral blood monocytes.
• Regulatory Status: RUO
• Gene ID (Entrez): 3689
• Content And Storage: Store at 4°C.
• Isotype: IgG2a

• Applications: Flow Cytometry
• Clone: IB4
• Description: Mouse monoclonal antibody raised against native ITGB2.
• Formulation: In 50mM sodium phosphate buffer, 100mM potassium chloride, 150mM NaCl, pH 7.5 (0.5mg/mL gentamicin sulfate)
• Gene Alias: CD18/LAD/LCAMB/LFA-1/MAC-1/MF17/MFI7
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid