ITGB4, Mouse, Clone: M126, Abnova™

Catalog No.	Quantity
89-110-387	100 μL

Catalog No. 89-110-387 Supplier Abnova Corporation Supplier No. MAB1371

Description

Mouse monoclonal antibody raised against partial recombinant ITGB4.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: ITGB4
• Applications: ELISA, Immunocytochemistry, Western Blot
• Classification: Monoclonal
• Clone: M126
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant ITGB4.
• Dilution: ELISA (1:2000) Immunocytochemistry (1:250) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
• Gene: ITGB4
• Gene Alias: CD104
• Gene Symbols: ITGB4
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to cytoplasmic region of human ITGB4.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3691
• Test Specificity: This sequence is found in all three integrin-beta 4 isoforms and has 90% homology with rat and mouse integrin-beta 4.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1