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MilliporeSigma™ Mouse anti-JAK2, Clone: 1C1,

Catalog No. MABS809MI Shop All MilliporeSigma Products
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MABS809MI 100 μL
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Mouse Monoclonal Antibody

Specifically detects JAK2 clone: 1C1 in Human samples, and it is validated for Western Blotting

Tyrosine-protein kinase JAK2 (JAK2) belongs to the protein kinase superfamily. JAK2 is involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis. Mutations in JAK2 have been associated with Budd-Chiari syndrome and Polycythemia vera.
TRUSTED_SUSTAINABILITY

Specifications

Antigen JAK2
Applications Western Blot
Classification Monoclonal
Clone 1C1
Formulation Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
Gene Accession No. O60674
Gene Symbols JAK2
Host Species Mouse
Immunogen Purified recombinant fragment of JAK2 expressed in E. coli
Purification Method Unpurified
Quantity 100 μL
Regulatory Status RUO
Research Discipline Signaling
Primary or Secondary Primary
Target Species Human
Content And Storage Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Form Ascites
Isotype IgG1
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For Research Use Only

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