Learn More
Description
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq
Specifications
Specifications
| Antigen | JAK3 |
| Applications | ELISA, Flow Cytometry, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 5H2 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant JAK3. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | JAK3 |
| Gene Alias | JAK-3/JAK3_HUMAN/JAKL/L-JAK/LJAK |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.