MilliporeSigma™ Mouse anti-KIF3A, Clone: 4F9.1,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABC155

Catalog No. MABC155MI

Description

Specifically detects KIF3A clone: 4F9.1 in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Western Blotting

Kinesin-like protein KIF3A (UniProt Q9Y496; also known as Kinesin family protein 3A, Microtubule plus end-directed kinesin motor 3A) is encoded by the KIF3A (also known as FLA10, KIF3, KLP-20) gene (Gene ID 11127) in human. Kinesin-2 is a heterotrimeric motor protein composed of two kinesin-related subunits, KIF3A and KIF3B, and an associated protein KAP3. The kinesin-2 motor KIF3A/B drives intraflagellar transport (IFT) of tubulins and other axonemal building blocks in cilia and flagella, pigment granules in melanosomes, and vesicles in neurons. Defects in these transport processes are linked to polycystic kidney disease and neurodegenerative diseases.

Specifications

• Antigen: KIF3A
• Classification: Monoclonal
• Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: KIF3; KIF3A
• Immunogen: KLH-conjugated linear peptide corresponding to the C-terminal of human KIF3A.
• Quantity: 100 μg
• Research Discipline: Apoptosis, Cancer
• Gene ID (Entrez): NP_001287720
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry, Western Blot
• Clone: 4F9.1
• Gene Accession No.: Q9Y496
• Host Species: Mouse
• Purification Method: Protein G Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Form: Purified

For Research Use Only