KLK3, Mouse, HRP, Clone: 5A6, Abnova™

Mouse monoclonal antibody raised against native KLK3.

Supplier:  Abnova Corporation MAB5475

Catalog No. 89-112-263

Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq

Specifications

• Antigen: KLK3
• Classification: Monoclonal
• Conjugate: HRP
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: KLK3
• Gene Symbols: KLK3
• Immunogen: Native purified KLK3 from human seminal plasma.
• Regulatory Status: RUO
• Gene ID (Entrez): 354
• Target Species: Human
• Form: Liquid

• Applications: ELISA
• Clone: 5A6
• Description: Mouse monoclonal antibody raised against native KLK3.
• Formulation: In PBS, pH 7.4 (50% glycerol, 5% BSA, 0.05% proclin 300)
• Gene Alias: APS/KLK2A1/PSA/hK3
• Host Species: Mouse
• Quantity: 1 mg
• Primary or Secondary: Primary
• Test Specificity: Specific for total PSA in equimolar determination, epitope 6. No cross-reactivity with human kallikrein 2.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2a