KRIT1, Mouse, Polyclonal Antibody, Abnova™

Catalog No.	Quantity
89-104-207	50 μL

Catalog No. 89-104-207 Supplier Abnova Corporation Supplier No. H00000889A01

Description

Mouse polyclonal antibody raised against a partial recombinant KRIT1.

This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq

Sequence: AAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYGCFMWQLGDTDTCFQIHSMENKMSFIVHTKQAGLVVKLLMKLNGQLMPTERNS

Specifications

• Antigen: KRIT1
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Conjugate: Unconjugated
• Description: Mouse polyclonal antibody raised against a partial recombinant KRIT1.
• Formulation: 50% glycerol
• Gene: KRIT1
• Gene Accession No.: NM_004912
• Gene Alias: CAM/CCM1
• Gene Symbols: KRIT1
• Host Species: Mouse
• Immunogen: KRIT1 (NP_004903, 637 a.a. ∽ 736 a.a) partial recombinant protein with GST tag.
• Quantity: 50 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 889
• Target Species: Human
• Content And Storage: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
• Form: Antisera

For Research Use Only