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Description
This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq
Specifications
Specifications
| Antigen | KRT10 |
| Applications | Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | LH2 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against KRT10. |
| Dilution | Flow Cytometry (0.5-1 ug/million cells) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (0.5-1 ug/mL for 30 min at RT) Immunoprecipitation (0.5-1 ug/500 ug protein lysate) Western Blot (0.25-0.5 ug/mL) The optimal working dilution sho |
| Formulation | In PBS, pH 7.4 (0.05% BSA, 0.05% sodium azide) |
| Gene | KRT10 |
| Gene Alias | CK10/K10/KPP |
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