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Lats2, Mouse, Clone: ST-3D10, Abnova™

Catalog No. 89107822 Shop All Abnova Corporation Products
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100 μg
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Catalog No. Quantity
89-107-822 100 μg
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Catalog No. 89-107-822 Supplier Abnova Corporation Supplier No. MAB0019

Description

Mouse monoclonal antibody raised against LATS2.

This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq

Specifications

Antigen Lats2
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone ST-3D10
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against LATS2.
Dilution Western Blot (1-2 ug/mL) Immunoprecipitation (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In 10mM HEPES/KOH, 150mM NaCl, pH 7.5 (50% glycerol)
Gene LATS2
Gene Accession No. NM_014572
Gene Alias FLJ13161/KPM
Gene Symbols LATS2
Host Species Mouse
Immunogen corresponding N-terminus portion of human Lats2., GST-Lats2N
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26524
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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