LCK, Mouse, Clone: 8E5F9, 4B2C7, Abnova™

Mouse monoclonal antibody raised against partial recombinant LCK.

Supplier:  Abnova Corporation MAB5528

Catalog No. 89-112-279

Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq

Specifications

• Antigen: LCK
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:2000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Gene: LCK
• Gene Symbols: LCK
• Immunogen: Recombinant protein corresponding to human LCK.
• Regulatory Status: RUO
• Gene ID (Entrez): 3932
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2a

• Applications: ELISA, Western Blot
• Clone: 4B2C7, 8E5F9
• Description: Mouse monoclonal antibody raised against partial recombinant LCK.
• Formulation: In ascites
• Gene Alias: YT16/p56lck/pp58lck
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid