LCK, Mouse, Clone: 8E5F9, 4B2C7, Abnova™

Catalog No.	Quantity
89-112-279	100 μL

Catalog No. 89-112-279 Supplier Abnova Corporation Supplier No. MAB5528

Description

Mouse monoclonal antibody raised against partial recombinant LCK.

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq

Specifications

• Antigen: LCK
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 4B2C7, 8E5F9
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant LCK.
• Dilution: Western Blot (1:500-1:2000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites
• Gene: LCK
• Gene Alias: YT16/p56lck/pp58lck
• Gene Symbols: LCK
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human LCK.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3932
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a