LEP, Mouse, Clone: 1E9 1H6, Abnova™

Catalog No.	Quantity
89-111-535	1 mg

Catalog No. 89-111-535 Supplier Abnova Corporation Supplier No. MAB3685

Description

Mouse monoclonal antibody raised against recombinant LEP.

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq

Specifications

• Antigen: LEP
• Applications: ELISA
• Classification: Monoclonal
• Clone: 1E9 1H6
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant LEP.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS
• Gene: LEP
• Gene Alias: FLJ94114/OB/OBS
• Gene Symbols: LEP
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human LEP.
• Quantity: 1 mg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3952
• Test Specificity: This antibody recognizes natural and recombinant human LEP.
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG1 κ