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LEP, Mouse, Clone: BDI142, Abnova™

Catalog No. 89111989 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-111-989 100 μL
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Catalog No. 89-111-989 Supplier Abnova Corporation Supplier No. MAB4845

Description

Mouse monoclonal antibody raised against synthetic peptide of LEP.

This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq

Specifications

Antigen LEP
Applications ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone BDI142
Conjugate Unconjugated
Description leptin
Formulation In ascites
Gene LEP
Gene Alias FLJ94114, OB, OBS
Gene Symbols LEP
Host Species Mouse
Immunogen A synthetic cyclized peptide corresponding to amino acids 92-145 of human LEP.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3952
Target Species Human
Content And Storage Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Ascites
Isotype IgG2a
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