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Description
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. [provided by RefSeq
Specifications
Specifications
| Antigen | LIMS1 |
| Applications | ELISA, Flow Cytometry, Immunofluorescence, Western Blot |
| Classification | Monoclonal |
| Clone | 5G7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant LIMS1. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | LIMS1 |
| Gene Alias | PINCH/PINCH1 |
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