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Description
This protein is the human homolog of mastermind, a Drosophila protein that plays a role in the Notch signaling pathway involved in cell-fate determination. There is in vitro evidence that the human homolog forms a complex with the intracellular portion of human Notch receptors and can increase expression of a Notch-induced gene. This evidence supports its proposed function as a transcriptional co-activator in the Notch signaling pathway. [provided by RefSeq
Specifications
Specifications
| Antigen | MAML1 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant MAML1. |
| Formulation | 50% glycerol |
| Gene | MAML1 |
| Gene Accession No. | NM_014757 |
| Gene Alias | KIAA0200/Mam-1/Mam1 |
| Gene Symbols | MAML1 |
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