MAP2K4, Mouse, Clone: 2D10D8, 4G11B2, Abnova™

Catalog No.	Quantity
89-112-283	100 μg

Catalog No. 89-112-283 Supplier Abnova Corporation Supplier No. MAB5532

Description

Mouse monoclonal antibody raised against partial recombinant MAP2K4.

This gene encodes a dual specificity protein kinase that belongs to the Ser/Thr protein kinase family. This kinase is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. It has been shown to activate MAPK8/JNK1, MAPK9/JNK2, and MAPK14/p38, but not MAPK1/ERK2 or MAPK3/ERK3. This kinase is phosphorylated, and thus activated by MAP3K1/MEKK. The knockout studies in mice suggested the roles of this kinase in mediating survival signal in T cell development, as well as in the organogenesis of liver. [provided by RefSeq

Specifications

• Antigen: MAP2K4
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 2D10D8, 4G11B2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant MAP2K4.
• Dilution: Western Blot (1:500-1:1000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (50% glycerol, 0.01% sodium azide)
• Gene: MAP2K4
• Gene Alias: JNKK/JNKK1/MAPKK4/MEK4/MKK4/PRKMK4/SEK1/SERK1
• Gene Symbols: MAP2K4
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human MAP2K4.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6416
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgM