MilliporeSigma™ Mouse anti-MAP2K6, Clone: 3H12C8,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABS810

Catalog No. MABS810MI

Description

Specifically detects MAP2K6 clone: 3H12C8 in Human, Mouse samples, and it is validated for ELISA, Flow Cytometry, Immunocytochemistry, Western Blotting

Dual specificity mitogen-activated protein kinase kinase 6 (MP2K6) is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. MP2K6 phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis.

Specifications

• Antigen: MAP2K6
• Classification: Monoclonal
• Formulation: Mouse monoclonal IgG1 ascitic fluid containing 0.03% sodium azide.
• Gene Symbols: MAP2K6; MEK6; MKK6; PRKMK6; SKK3
• Immunogen: Purified recombinant fragment of human MAP2K6 expressed in E. coli.
• Quantity: 100 μL
• Research Discipline: Signaling
• Target Species: Human, Mouse
• Form: Ascites

• Applications: ELISA, Flow Cytometry, Immunocytochemistry, Western Blot
• Clone: 3H12C8
• Gene Accession No.: P52564
• Host Species: Mouse
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
• Isotype: IgG1

For Research Use Only