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  6. Mouse anti-MCAM/CD146, Clone: OJ79c, Azide Free, Novus Biologicals™

Mouse anti-MCAM/CD146, Clone: OJ79c, Azide Free, Novus Biologicals™
SDP

Catalog No. p-5324237 Shop All R&D Systems Products
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0.2 mg
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Catalog No. Quantity
NBP23470102 0.2 mg
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Catalog No. NBP23470102 Supplier Novus Biologicals Supplier No. NBP2347010.2 MG

Description

Mouse Monoclonal Antibody

MCAM/CD146 Monoclonal antibody specifically detects MCAM/CD146 in Human samples. It is validated for Western Blot, Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, CyTOF-ready.

Specifications

Antigen MCAM/CD146
Applications Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Frozen)
Classification Monoclonal
Clone OJ79c
Concentration 1.0 mg/mL
Conjugate Unconjugated
Dilution Western Blot 0.5-1.0ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1.0ug/ml, Immunoprecipitation 1-2ug/500ug protein, Immunohistochemistry-Frozen 0.5-1ug/ml, CyTOF-ready
Formulation 10mM PBS - BSA free with No Preservative
Gene Accession No. P43121
Gene Alias CD146, CD146 antigen, cell surface glycoprotein MUC18, Cell surface glycoprotein P1H12, melanoma adhesion molecule, melanoma cell adhesion moleculeS-endo 1 endothelial-associated antigen, Melanoma-associated antigen A32, Melanoma-associated antigen MUC18, MUC18Gicerin
Gene Symbols MCAM
Host Species Mouse
Immunogen Recombinant human MUC18 protein
Molecular Weight of Antigen 130 kDa
Purification Method Protein A purified
Quantity 0.2 mg
Regulatory Status RUO
Research Discipline Cancer, Mesenchymal Stem Cell Markers, Phospho Specific, Stem Cell Markers
Primary or Secondary Primary
Gene ID (Entrez) 4162
Test Specificity The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
Reconstitution Protein A purified
Target Species Human
Content And Storage Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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