MDM4, Mouse, Clone: 15, Abnova™

Catalog No.	Quantity
89-113-025	100 μg

Catalog No. 89-113-025 Supplier Abnova Corporation Supplier No. MAB6760

Description

Mouse monoclonal antibody raised against synthetic phosphopeptide of MDM4.

The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene. [provided by RefSeq

Specifications

• Antigen: MDM4
• Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: #15
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic phosphopeptide of MDM4.
• Dilution: Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In antiserum (0.05% sodium azide)
• Gene: MDM4
• Gene Alias: DKFZp781B1423/HDMX/MDMX/MGC132766/MRP1
• Gene Symbols: MDM4
• Host Species: Mouse
• Immunogen: Synthetic phosphopeptide corresponding to residues surrounding S367 of human MDM4.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4194
• Test Specificity: This antibody reacts with MDM4 phosphorylated at Ser367.
• Target Species: Human, Mouse
• Content And Storage: Store at -20°C. For long term storage store at -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b κ