MDM4, Mouse, Clone: 2D10F4, Abnova™

Mouse monoclonal antibody raised against recombinant MDM4.

Supplier:  Abnova Corporation MAB10353

Catalog No. 89-108-540

Description

The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene. [provided by RefSeq

Specifications

• Antigen: MDM4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Gene: MDM4
• Gene Symbols: MDM4
• Immunogen: Recombinant protein corresponding to human MDM4.
• Regulatory Status: RUO
• Gene ID (Entrez): 4194
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Clone: 2D10F4
• Description: Mouse monoclonal antibody raised against recombinant MDM4.
• Formulation: In ascites (0.03% sodium azide)
• Gene Alias: DKFZp781B1423/HDMX/MDMX/MGC132766/MRP1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid