MDM4, Mouse, Clone: 2D10F4, Abnova™

Catalog No.	Quantity
89-108-540	100 μL

Catalog No. 89-108-540 Supplier Abnova Corporation Supplier No. MAB10353

Description

Mouse monoclonal antibody raised against recombinant MDM4.

The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene. [provided by RefSeq

Specifications

• Antigen: MDM4
• Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 2D10F4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant MDM4.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: MDM4
• Gene Alias: DKFZp781B1423/HDMX/MDMX/MGC132766/MRP1
• Gene Symbols: MDM4
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human MDM4.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4194
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1