MilliporeSigma™ Mouse anti-MLN64/STARD3, Clone: 2BE-2F4,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ MABS1283

Catalog No. MABS1283MI

Description

Specifically detects MLN64/STARD3 clone: 2BE-2F4 in Human samples, and it is validated for Immunohistochemistry, Western Blotting

MLN64/StARD3 (also known as es64, StAR-related lipid transfer protein 3, Metastatic lymph node gene 64 protein, Metastatic lymph node protein 64, StARD3, START domain-containing protein 3, Steroidogenic acute regulatory protein related; UniProt Q14849) is encoded by the MLN64 (or CAB1 & STARD3) gene in human (NCBI Gene ID 10948). MLN64/StARD3 is a late endosome (LE) multitransmembrane protein that plays an important role in intracellular cholesterol transport and steroidogenesis. In addition to binding cholesterol via its C-terminal STAR domain, MLN64/StARD3 is reported to interact with ER-anchored VAP proteins via a conserved motif called 'two phenylalanines in an acidic tract' or FFAT, thereby forming an LE-ER tethering complex at the inter-organelle membrane contacts sites (MCSs), allowing heterologous membrane apposition and the exchange of metabolites (PMID 23709693 and 24105263). Clone 2BE-2F4 is also known as 2BE2F4 and mAbMLN64-Ct, it detects an epitope within the c-terminal region encompassing the last 20% of MLN64 sequence.

Specifications

• Antigen: MLN64/STARD3
• Classification: Monoclonal
• Formulation: Mouse monoclonal IgG1κ ascites with 0.05% sodium azide.
• Gene Symbols: STARD3; CAB1; MLN64
• Immunogen: Ovalbumin-conjugated linear peptide corresponding to human MLN64/STARD3 near the C-terminus.
• Quantity: 100 μL
• Research Discipline: Signaling
• Gene ID (Entrez): NP_001159409
• Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
• Isotype: IgG1 κ

• Applications: Immunohistochemistry, Western Blot
• Clone: 2BE-2F4
• Gene Accession No.: Q14849
• Host Species: Mouse
• Purification Method: Unpurified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Form: Ascites

For Research Use Only