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MME, Mouse, Clone: CB-Calla, Abnova™

Catalog No. 89113487 Shop All Abnova Corporation Products
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89-113-487 100 μg
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Catalog No. 89-113-487 Supplier Abnova Corporation Supplier No. MAB8549
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Description

Mouse monoclonal antibody raised against full-length native MME.

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100kDa type II transmembrane glycoprotein, exists in a single copy of greater than 45kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq]

Specifications

Antigen MME
Applications Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation
Classification Monoclonal
Clone CB-Calla
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against full length native MME.
Dilution Flow cytometry (1 ug/106 cells) The optimal working dilution should be determined by the end user.
Formulation In BBS, pH 8.2
Gene MME
Gene Alias CALLA/CD10/DKFZp686O16152/MGC126681/MGC126707/NEP
Gene Symbols MME
Host Species Mouse
Immunogen Native pufiried MME from human B-lineage leukemia cells.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4311
Test Specificity This antibody is specific to MME.
Target Species Human
Content And Storage Store at 4°C.
Form Liquid
Isotype IgG2b
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