MME, Mouse, PerCP, Clone: MEM-78, Abnova™

Catalog No.	Quantity
89-111-929	100 Reactions

Catalog No. 89-111-929 Supplier Abnova Corporation Supplier No. MAB4609

Description

Mouse monoclonal antibody raised against native MME.

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100kDa type II transmembrane glycoprotein, exists in a single copy of greater than 45kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq]

Specifications

• Antigen: MME
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: MEM-78
• Conjugate: PerCP
• Description: Mouse monoclonal antibody raised against native MME.
• Dilution: Flow Cytometry (10 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: MME
• Gene Alias: CALLA/CD10/DKFZp686O16152/MGC126681/MGC126707/NEP
• Gene Symbols: MME
• Host Species: Mouse
• Immunogen: Native purified MME from NALM-6 human pre-B cell line.
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4311
• Test Specificity: This antibody reacts with CD10 antigen (CALLA - Common acute lymphatic leukemia antigen), a 100 KDa type II integral membrane protein.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1