MMP2, Mouse, Clone: 4D3, Abnova™

Catalog No.	Quantity
89-109-309	200 μg

Catalog No. 89-109-309 Supplier Abnova Corporation Supplier No. MAB11117

Description

Mouse monoclonal antibody raised against recombinant protein of human MMP2.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: MMP2
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 4D3
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant protein of human MMP2.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.01% sodium azide)
• Gene: MMP2
• Gene Alias: CLG4/CLG4A/MMP-II/MONA/TBE-1
• Gene Symbols: MMP2
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to C-terminus of human MMP2.
• Purification Method: Protein A/G purification
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4313
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1