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MMP2, Mouse, Clone: MMP2/8B4, Abnova™

Catalog No. 89110939 Shop All Abnova Corporation Products
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89-110-939 100 μL
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Catalog No. 89-110-939 Supplier Abnova Corporation Supplier No. MAB2335
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Description

Mouse monoclonal antibody raised against recombinant MMP2.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

Antigen MMP2
Applications ELISA, Immunohistochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone MMP2/8B4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant MMP2.
Dilution ELISA (0.3 ug/mL) Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2 ug/mL) Immunohistochemistry (Frozen sections) (2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In PBS (0.05% sodium azide)
Gene MMP2
Gene Alias CLG4/CLG4A/MMP-II/MONA/TBE-1
Gene Symbols MMP2
Host Species Mouse
Immunogen Recombinant protein corresponding to human MMP2.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4313
Test Specificity This antibody is specific to pro and active MMP2.
Target Species Human, Mouse, Rat
Content And Storage Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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