CD157 Mouse anti-Mouse, Brilliant Violet 786, Clone: BP-3, BD Optibuild™
Mouse Monoclonal Antibody
Manufacturer: BD Biosciences 741012
The BP-3 antibody reacts with CD157, also known as the BP-3 alloantigen or Bone marrow ST romal cell antigen- 1 (BST-1), found in a variety of common laboratory strains of mice (AKR, BALB/c, CBA/N, C3H/HeJ, C57BL/6, DBA/2, NZB, C.B-17, SJL and Swiss, but not A/J). CD157 is a differentially glycosylated GPI-linked cell-surface glycoprotein with a core protein of 32 kDa and differing patterns of glycosylation in different types of cells. It is a member, along with CD38, of a family of genetically-related ectoenzymes. The BP-3 alloantigen is expressed on the B lineage from the earliest detectable progenitors to circulating immature B lymphocytes, on immature thymocytes up to the expression of the T-cell receptor, on circulating neutrophils, peritoneal macrophages, on subpopulations of stromal cells in peripheral lymphoid organs (but not in bone marrow or thymus), on intestinal epithelial cells, and in the lumen of kidney-collecting tubules. The distribution of CD157 antigen on leukocytes and stromal cells of lymphoid organs suggests that it may be involved in leukocyte-stroma interactions which support the development, migration, and/or responses of leukocyte populations.
|Brilliant Violet 786|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|IgG2b, κ, also known as STF Mus spretus IgG2b, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
|Mouse pre-B cell line|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok
For Research Use Only