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Description
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. [provided by RefSeq]
Specifications
Specifications
| Antigen | MSH2 |
| Applications | ELISA, Immunofluorescence, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 1B3 (3A2B8C) |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant MSH2. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | MSH2 |
| Gene Alias | COCA1/FCC1/HNPCC/HNPCC1/LCFS2 |
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