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Description
An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq
Specifications
Specifications
| Antigen | MSLN |
| Applications | ELISA, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | MN-1 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant MSLN. |
| Dilution | Western Blot (1:1000) Immunohistochemistry (1:100) The optimal working dilution should be determined by the end user. |
| Formulation | In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide) |
| Gene | MSLN |
| Gene Alias | CAK1/MPF/SMR |
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