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MUC1, Mouse, Clone: ABN-17, Abnova™

Catalog No. 89108980 Shop All Abnova Corporation Products
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89-108-980 1 mL
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Catalog No. 89-108-980 Supplier Abnova Corporation Supplier No. MAB10778
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Description

Mouse monoclonal antibody raised against MUC1.

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq

Specifications

Antigen MUC1
Applications Immunohistochemistry
Classification Monoclonal
Clone ABN-17
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against MUC1.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (protein base, 0.09% sodium azide)
Gene MUC1
Gene Alias CD227/EMA/H23AG/MAM6/PEM/PEMT/PUM
Gene Symbols MUC1
Host Species Mouse
Immunogen MUC1.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4582
Target Species Human
Content And Storage Store at 4°C is stable for 3 years.
Form Liquid
Isotype IgG1
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