MUC1, Mouse, Clone: SPM492, Abnova™

Catalog No.	Quantity
89-110-833	100 μL

Catalog No. 89-110-833 Supplier Abnova Corporation Supplier No. MAB2126

Description

Mouse monoclonal antibody raised against native MUC1.

This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq

Specifications

• Antigen: MUC1
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Monoclonal
• Clone: SPM492
• Concentration: Lot specific
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native MUC1.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:100) The optimal working dilution should be determined by the end user.
• Formulation: In 10mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
• Gene: MUC1
• Gene Alias: CD227/EMA/H23AG/MAM6/PEM/PEMT/PUM
• Gene Symbols: MUC1
• Host Species: Mouse
• Immunogen: Native purified MUC1 from human breast cell line ZR-75-1.
• Purification Method: Protein G purification
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4582
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG1 κ