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MUSK, Mouse, Clone: 10A4, Abnova™

Catalog No. 89108614 Shop All Abnova Corporation Products
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Catalog No. Quantity
89-108-614 100 μL
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Catalog No. 89-108-614 Supplier Abnova Corporation Supplier No. MAB10428
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Description

Mouse monoclonal antibody raised against recombinant MUSK.

Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM

Specifications

Antigen MUSK
Applications ELISA, Immunofluorescence, Immunohistochemistry
Classification Monoclonal
Clone 10A4
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant MUSK.
Dilution Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
Formulation In ascitic (0.03% sodium azide)
Gene MUSK
Gene Alias MGC126323/MGC126324
Gene Symbols MUSK
Host Species Mouse
Immunogen Recombinant protein corresponding to human MUSK.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4593
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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