MYC, Mouse, Clone: 2B2, Abnova™

Catalog No.	Quantity
89-113-864	100 μg

Catalog No. 89-113-864 Supplier Abnova Corporation Supplier No. MAB9906

Description

Mouse monoclonal antibody raised against synthetic peptide of MYC.

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]

Specifications

• Antigen: MYC
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 2B2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of MYC.
• Dilution: Western blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
• Gene: MYC
• Gene Accession No.: NM_002467
• Gene Alias: bHLHe39/c-Myc
• Gene Symbols: MYC
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to amino acids 408-420 at C-terminus of human MYC.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4609
• Test Specificity: It recognizes MYC and MYC tagged fusion proteins.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1